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SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 15 Reviews
8.7
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B₁₂ (as Methylcobalamin)
1,000 mcg
41,667%
Top Medical Research Studies
8
Vitamin B12 reduces cardiovascular risks
Association of MTHFR C677T, MTHFRA1298C, and MTRRA66G Gene Polymorphisms with Hyperhomocysteinemia and Its Modulation by the Combined Effect of Vitamin B12 and Folate in Chinese Population with Hypertension.
Moderate relevance to findings
We explored the connection between vitamin B12, genetic factors, and cardiovascular health in a group of Chinese adults suffering from hypertension. By analyzing the genetic variations of individuals, we aimed to understand how these may influence levels of homocysteine, an amino acid that can impact heart health when present in high amounts.
Our study included 1,304 participants over the age of 18. We measured their serum levels of vitamin B12 and folate, as well as their total homocysteine concentrations. The findings were quite significant: adequate levels of both vitamin B12 and folate were linked to lower homocysteine levels. This suggests that ensuring proper nutrition might be key to managing cardiovascular risks associated with high homocysteine.
We also noticed that the genotypic effects on homocysteine levels could be lessened with sufficient intake of these vitamins. Targeted nutritional interventions, such as increasing vitamin B12 and folate in the diet, could therefore play an essential role in heart health for those at risk. Our results emphasize the importance of nutrition in supporting cardiovascular health and managing hypertension.
Our study included 1,304 participants over the age of 18. We measured their serum levels of vitamin B12 and folate, as well as their total homocysteine concentrations. The findings were quite significant: adequate levels of both vitamin B12 and folate were linked to lower homocysteine levels. This suggests that ensuring proper nutrition might be key to managing cardiovascular risks associated with high homocysteine.
We also noticed that the genotypic effects on homocysteine levels could be lessened with sufficient intake of these vitamins. Targeted nutritional interventions, such as increasing vitamin B12 and folate in the diet, could therefore play an essential role in heart health for those at risk. Our results emphasize the importance of nutrition in supporting cardiovascular health and managing hypertension.
Read More
7
Vitamin deficiencies affect blood pressure
The impact of folic acid/VB12 deficiency on essential hypertension in children and adolescents: from a nested case-control and a cohort study.
Significant findings on hypertension
We set out to understand how serum folic acid (FA) and vitamin B12 (VB12) levels relate to elevated blood pressure in children and adolescents. Our research included both a nested case-control and a cohort study, focusing on participants from primary schools. We observed that participants with elevated blood pressure had notably lower levels of folic acid and vitamin B12 compared to those with normal blood pressure.
Moreover, these children also had higher levels of homocysteine, a substance that can be harmful in excessive amounts. Among those who were overweight and obese, we found that those with high blood pressure had even lower levels of folic acid. The data suggested a significant connection: higher levels of folic acid were associated with better blood pressure outcomes, and this relationship remained even after accounting for vitamin B12 and homocysteine levels.
Additionally, our cohort study highlighted that both systolic and diastolic blood pressure measurements were lower in children with high folic acid exposure compared to those with low exposure. Overall, our findings indicated that deficiencies in folic acid and vitamin B12 during childhood can contribute to elevated blood pressure, potentially influencing cardiovascular health. Therefore, it's important to ensure adequate intake of these vitamins, either through diet or supplementation.
Moreover, these children also had higher levels of homocysteine, a substance that can be harmful in excessive amounts. Among those who were overweight and obese, we found that those with high blood pressure had even lower levels of folic acid. The data suggested a significant connection: higher levels of folic acid were associated with better blood pressure outcomes, and this relationship remained even after accounting for vitamin B12 and homocysteine levels.
Additionally, our cohort study highlighted that both systolic and diastolic blood pressure measurements were lower in children with high folic acid exposure compared to those with low exposure. Overall, our findings indicated that deficiencies in folic acid and vitamin B12 during childhood can contribute to elevated blood pressure, potentially influencing cardiovascular health. Therefore, it's important to ensure adequate intake of these vitamins, either through diet or supplementation.
Read More
Most Useful Reviews
9.5
Eased symptoms effectively
This product has alleviated my severe folic acid and B12 deficiency symptoms, such as numbness and muscle pain. Unlike injections, these easy-to-take pills have shown remarkable results. I feel energised, and the sweet taste makes it enjoyable. I highly recommend it for overall well-being.
Read More
9
Improves overall vitality
I switched to methylcobalamin for easier absorption without straining my liver. Dissolving the lozenges quickly delivers the vitamin, enhancing my energy levels and reducing fatigue, which could also help mitigate risks associated with cardiovascular disease.
Read More
9.5
Essential for elderly
This wonderful complex of B vitamins (B12, B6, B9) is crucial for managing chronic viral loads and homocysteine levels, which directly reduces the risk of cardiovascular disease, particularly in the elderly. I find its quality impressive.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
8
Vitamin B12 reduces cardiovascular risks
Association of MTHFR C677T, MTHFRA1298C, and MTRRA66G Gene Polymorphisms with Hyperhomocysteinemia and Its Modulation by the Combined Effect of Vitamin B12 and Folate in Chinese Population with Hypertension.
Moderate relevance to findings
We explored the connection between vitamin B12, genetic factors, and cardiovascular health in a group of Chinese adults suffering from hypertension. By analyzing the genetic variations of individuals, we aimed to understand how these may influence levels of homocysteine, an amino acid that can impact heart health when present in high amounts.
Our study included 1,304 participants over the age of 18. We measured their serum levels of vitamin B12 and folate, as well as their total homocysteine concentrations. The findings were quite significant: adequate levels of both vitamin B12 and folate were linked to lower homocysteine levels. This suggests that ensuring proper nutrition might be key to managing cardiovascular risks associated with high homocysteine.
We also noticed that the genotypic effects on homocysteine levels could be lessened with sufficient intake of these vitamins. Targeted nutritional interventions, such as increasing vitamin B12 and folate in the diet, could therefore play an essential role in heart health for those at risk. Our results emphasize the importance of nutrition in supporting cardiovascular health and managing hypertension.
Our study included 1,304 participants over the age of 18. We measured their serum levels of vitamin B12 and folate, as well as their total homocysteine concentrations. The findings were quite significant: adequate levels of both vitamin B12 and folate were linked to lower homocysteine levels. This suggests that ensuring proper nutrition might be key to managing cardiovascular risks associated with high homocysteine.
We also noticed that the genotypic effects on homocysteine levels could be lessened with sufficient intake of these vitamins. Targeted nutritional interventions, such as increasing vitamin B12 and folate in the diet, could therefore play an essential role in heart health for those at risk. Our results emphasize the importance of nutrition in supporting cardiovascular health and managing hypertension.
Read More
7
Vitamin deficiencies affect blood pressure
The impact of folic acid/VB12 deficiency on essential hypertension in children and adolescents: from a nested case-control and a cohort study.
Significant findings on hypertension
We set out to understand how serum folic acid (FA) and vitamin B12 (VB12) levels relate to elevated blood pressure in children and adolescents. Our research included both a nested case-control and a cohort study, focusing on participants from primary schools. We observed that participants with elevated blood pressure had notably lower levels of folic acid and vitamin B12 compared to those with normal blood pressure.
Moreover, these children also had higher levels of homocysteine, a substance that can be harmful in excessive amounts. Among those who were overweight and obese, we found that those with high blood pressure had even lower levels of folic acid. The data suggested a significant connection: higher levels of folic acid were associated with better blood pressure outcomes, and this relationship remained even after accounting for vitamin B12 and homocysteine levels.
Additionally, our cohort study highlighted that both systolic and diastolic blood pressure measurements were lower in children with high folic acid exposure compared to those with low exposure. Overall, our findings indicated that deficiencies in folic acid and vitamin B12 during childhood can contribute to elevated blood pressure, potentially influencing cardiovascular health. Therefore, it's important to ensure adequate intake of these vitamins, either through diet or supplementation.
Moreover, these children also had higher levels of homocysteine, a substance that can be harmful in excessive amounts. Among those who were overweight and obese, we found that those with high blood pressure had even lower levels of folic acid. The data suggested a significant connection: higher levels of folic acid were associated with better blood pressure outcomes, and this relationship remained even after accounting for vitamin B12 and homocysteine levels.
Additionally, our cohort study highlighted that both systolic and diastolic blood pressure measurements were lower in children with high folic acid exposure compared to those with low exposure. Overall, our findings indicated that deficiencies in folic acid and vitamin B12 during childhood can contribute to elevated blood pressure, potentially influencing cardiovascular health. Therefore, it's important to ensure adequate intake of these vitamins, either through diet or supplementation.
Read More
User Reviews
USERS' SCORE
Good
Based on 15 Reviews
8.7
9.5
Eased symptoms effectively
This product has alleviated my severe folic acid and B12 deficiency symptoms, such as numbness and muscle pain. Unlike injections, these easy-to-take pills have shown remarkable results. I feel energised, and the sweet taste makes it enjoyable. I highly recommend it for overall well-being.
Read More
9.5
Essential for elderly
This wonderful complex of B vitamins (B12, B6, B9) is crucial for managing chronic viral loads and homocysteine levels, which directly reduces the risk of cardiovascular disease, particularly in the elderly. I find its quality impressive.
9.5
Prevents health issues
This bioidentical methylcobalamin vitamin B12 is essential for maintaining brain and nerve health, with severe deficiencies leading to various health problems including those affecting cardiovascular disease. It has improved my sleep quality, enhancing overall life quality.
9.5
Increased energy
An excellent vitamin B12 in the form of methylcobalamin. I had a deficiency contributing to my anaemia, and after taking this supplement, I felt much better and had more energy. My constant fatigue disappeared. I look forward to retesting after my treatment course.
9.3
Improves cognitive function
I often recommend Jarrow Formulas Methyl B12 to my clients due to its superior absorption and positive effects on the nervous system. Adequate B12 levels help combat fatigue, boost mood, and lower homocysteine, a risk factor in cardiovascular disease. The chewable tablets are a convenient choice.
Read More
